The show is set in the nearby regions of the Milky Way galaxy, roughly during the 2150s—ten years before the United Federation of Planets shown in previous Star Trek series was formed. It follows the adventures of humanity's first warp 5 starship Enterprise.
Enterprise premiered on September 26, 2001. The pilot episode, "Broken Bow", takes place in the year 2151, halfway between the 21st-century events shown in the movie Star Trek: First Contact and the original Star Trek television series. Low ratings prompted UPN to cancel Star Trek: Enterprise on February 2, 2005, but the network allowed the series to complete its fourth season. The final episode aired on May 13, 2005. After a run of four seasons and 98 episodes, it was the first Star Trek series since the original Star Trek to have been canceled by its network rather than finished by its producers. It is also the last series in an 18-year run of back-to-back new Star Trek shows beginning with Star Trek: The Next Generation in 1987.
Read more about Star Trek: Enterprise: Production, Cast of Characters, Cancellation, Reception