South Central Pennsylvania is a region of the U.S. state of Pennsylvania that includes the fourteen counties of Adams, Cumberland, Dauphin, Franklin, Huntingdon, Juniata, Lancaster, Lebanon, Mifflin, Northumberland (southwestern parts), Perry, Schuylkill (extreme western parts only), Snyder, and York. Lancaster is the largest city in the region. Harrisburg with 49,528 people is the second largest city in the region, but with a metropolitan area of 643,820 people, and is the capital of all of Pennsylvania. Lancaster and York are the other two significant cities in the region. The Harrisburg-Lancaster-York television market (which formally includes Adams, Cumberland, Dauphin, Juniata, Lancaster, Lebanon, Mifflin, Perry, and York Counties) is the 39th largest market in the United States.
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