Silv

SILV

Identifiers Symbols PMEL; D12S53E; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV; gp100 External IDs OMIM: 155550 MGI: 98301 HomoloGene: 5048 GeneCards: PMEL Gene

Gene Ontology
Molecular function	• protein binding
Cellular component	• extracellular region • endoplasmic reticulum membrane • Golgi apparatus • plasma membrane • integral to membrane • multivesicular body membrane • melanosome
Biological process	• melanosome organization • melanin biosynthetic process
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 6490 20431 Ensembl ENSG00000185664 ENSMUSG00000025359 UniProt P40967 Q9CZB2 RefSeq (mRNA) NM_001200053 NM_021882 RefSeq (protein) NP_001186982 NP_068682 Location (UCSC) Chr 12:
56.35 – 56.37 Mb Chr 10:
128.71 – 128.72 Mb PubMed search

"Gp100" redirects here. For the firearm, see Ruger GP100.

Melanocyte protein PMEL also known as premelanosome protein (PMEL) or silver locus protein homolog (SILV) is a protein that in humans is encoded by the PMEL gene. Its gene product may be referred to as PMEL, silver, ME20, gp100 or Pmel17.