Target For Drugs
Shikimate can be used to synthesise (6S)-6-Fluoroshikimic acid, an antibiotic which inhibits the aromatic biosynthetic pathway.
Glyphosate, the active ingredient in the herbicide Roundup, kills plants by interfering with the shikimate pathway in plants. More specifically, glyphosate inhibits the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). "Roundup Ready" genetically modified crops overcome that inhibition.
Read more about this topic: Shikimic Acid
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—Spike Lee (b. 1956)