Professional Boxing Record
| 46 Wins (39 knockouts, 7 decisions), 8 losses (0 knockouts, 8 decisions), 1 Draw, 1 No Contest | |||||||
| Res. | Record | Opponnent | Type | Round | Date | Location | Notes |
| Loss | 46-8-1 | Saúl Álvarez | UD | 12 | 2012-05-05 | MGM Grand Garden Arena, Las Vegas, Nevada | For WBC Light Middleweight title. |
| Loss | 46-7-1 | Manny Pacquiao | UD | 12 | 2011-05-07 | MGM Grand Garden Arena, Las Vegas, Nevada | For WBO Welterweight title. |
| Draw | 46-6-1 | Sergio Mora | SD | 12 | 2010-09-18 | Staples Center, Los Angeles, California | |
| Loss | 46-6 | Floyd Mayweather, Jr. | UD | 12 | 2010-05-01 | MGM Grand Garden Arena, Las Vegas, Nevada | |
| Win | 46-5 | Antonio Margarito | TKO | 9 (12), 0:43 | 2009-01-24 | Staples Center, Los Angeles, California | Won WBA (Super) Welterweight title. |
| Win | 45-5 | Ricardo Mayorga | KO | 12 (12), 2:59 | 2008-09-27 | The Home Depot Center, Carson, California | Won vacant WBA Inter-Continental Light Middleweight title. |
| Loss | 44-5 | Miguel Cotto | UD | 12 | 2007-11-10 | Madison Square Garden, New York, New York | For WBA Welterweight title. |
| Win | 44-4 | Luis Collazo | UD | 12 | 2007-02-10 | MGM Grand Garden Arena, Las Vegas, Nevada | Won Interim WBC Welterweight title. |
| Win | 43-4 | Fernando Vargas | TKO | 6 (12), 2:38 | 2006-07-15 | MGM Grand Garden Arena, Las Vegas, Nevada | |
| Win | 42-4 | Fernando Vargas | TKO | 10 (12), 1:22 | 2006-02-25 | Mandalay Bay Events Center, Las Vegas, Nevada | WBA Light Middleweight Title Eliminator. |
| Win | 41-4 | José Luis Cruz | UD | 10 | 2005-09-17 | MGM Grand Garden Arena, Las Vegas, Nevada | |
| Win | 40-4 | David Estrada | UD | 10 | 2005-04-23 | Caesars Palace, Las Vegas, Nevada | |
| Loss | 39-4 | Winky Wright | MD | 12 | 2004-11-20 | Mandalay Bay Events Center, Las Vegas, Nevada | For The Ring, WBC & WBA (Super) Light Middleweight titles. |
| Loss | 39-3 | Winky Wright | UD | 12 | 2004-03-13 | Mandalay Bay Events Center, Las Vegas, Nevada | Lost The Ring, WBC & WBA (Super) Light Middleweight titles. For IBF Light Middleweight title. |
| Win | 39-2 | Oscar De La Hoya | UD | 12 | 2003-09-13 | MGM Grand Garden Arena, Las Vegas, Nevada | Won The Ring, WBC, WBA (Super) & IBA Light Middleweight titles. |
| NC | 1 NC | Raúl Márquez | NC | 3 (12), 2:41 | 2003-02-08 | Mandalay Bay Events Center, Las Vegas, Nevada | |
| Loss | 38-2 | Vernon Forrest | UD | 12 | 2002-07-20 | Conseco Fieldhouse, Indianapolis, Indiana | For The Ring & WBC Welterweight titles. |
| Loss | 38-1 | Vernon Forrest | UD | 12 | 2002-01-26 | Madison Square Garden, New York, New York | Lost WBC Welterweight title. For vacant The Ring Welterweight title. |
| Win | 38-0 | Adrian Stone | TKO | 3 (12), 2:01 | 2001-07-21 | Caesars Palace, Las Vegas, Nevada | Retained WBC Welterweight title. |
| Win | 37-0 | Shannan Taylor | TKO | 6 (12), 3:00 | 2001-03-10 | Caesars Palace, Las Vegas, Nevada | Retained WBC Welterweight title. |
| Win | 36-0 | Antonio Diaz | TKO | 6 (12), 1:36 | 2000-11-04 | Madison Square Garden, New York, New York | Retained WBC Welterweight title. |
| Win | 35-0 | Oscar De La Hoya | SD | 12 | 2000-06-17 | Staples Center, Los Angeles, California | Won WBC & IBA Welterweight title. |
| Win | 34-0 | Willy Wise | TKO | 3 (10), 2:28 | 2000-01-22 | Hard Rock Hotel & Casino, Las Vegas, Nevada | |
| Win | 33-0 | Wilfredo Rivera | KO | 10 (10), 2:38 | 1999-09-25 | Pechanga Resort & Casino, Temecula, California | |
| Win | 32-0 | John Brown | TKO | 8 (12), 3:00 | 1999-04-17 | Fantasy Springs Resort & Casino, Indio, California | Retained IBF Lightweight title. |
| Win | 31-0 | Golden Johnson | KO | 7 (12), 2:59 | 1999-01-09 | Pensacola Civic Center, Pensacola, Florida | Retained IBF Lightweight title. |
| Win | 30-0 | Jesse James Leija | TKO | 9 (12), 3:00 | 1998-11-14 | Foxwoods Resort Casino, Mashantucket, Connecticut | Retained IBF Lightweight title. |
| Win | 29-0 | Eduardo Morales | TKO | 5 (12), 2:06 | 1998-09-22 | Madison Square Garden, New York, New York | Retained IBF Lightweight title. |
| Win | 28-0 | Wilfredo Ruiz | KO | 5 (12), 2:32 | 1998-06-27 | Apollo Theatre, Philadelphia, Pennsylvania | Retained IBF Lightweight title. |
| Win | 27-0 | John John Molina | TKO | 8 (12), 2:27 | 1998-05-09 | Trump Taj Mahal, Atlantic City, New Jersey | Retained IBF Lightweight title. |
| Win | 26-0 | Demetrio Ceballos | TKO | 8 (12), 2:34 | 1998-02-06 | Mohegan Sun, Uncasville, Connecticut | Retained IBF Lightweight title. |
| Win | 25-0 | Manuel Gomez | KO | 11 (12), 1:25 | 1997-11-25 | County Coliseum, El Paso, Texas | Retained IBF Lightweight title. |
| Win | 24-0 | Philip Holiday | UD | 12 | 1997-08-02 | Mohegan Sun, Uncasville, Connecticut | Won IBF Lightweight title. |
| Win | 23-0 | Michael Smith | KO | 4 (10) | 1997-04-09 | Inland Expo Center, Westmont, Illinois | |
Read more about this topic: Shane Mosley
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