Prelude
After its independence from Spain on November 28, 1821, Panama became a part of the Republic of Gran Colombia which consisted of today's Colombia, Venezuela, Panama and Ecuador.
The political struggle between federalists and centralists that followed independence from Spain resulted in a changing administrative and jurisdictional status for Panama. Under centralism Panama was established as the Department of the Isthmus and during the federalism as Sovereign State of Panama.
Read more about this topic: Separation Of Panama From Colombia
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—Friedrich Nietzsche (1844–1900)