Scavenger Receptor - Types

Types

Scavenger receptors are categorized into classes A, B, and C according to their structural characteristics.

  • Class A is mainly expressed in the macrophage, and a protein whose molecular weight is about 80 kDa makes a trimer; it is composed of 1) cytosol domain, 2) transmembrane domain, 3) spacer domain, 4) alpha-helical coiled-coil domain, 5) collagen-like domain, and 6) cysteine-rich domain.
  • Class B has two transmembrane regions.
  • Class C is a transmembrane protein whose N-terminus is located extracellularly.

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