Function
It is thought that scavenger receptors participate in the removal of many foreign substances and waste materials in the living body by extensive ligand specificity and a variety of receptor molecules.
In atherosclerotic lesions, macrophages that express scavenger receptors on their plasma membrane aggressively uptake the oxidized LDL deposited in the blood vessel wall inside and become foam cells, and they secrete various inflammatory cytokines and accelerate the development of atherosclerosis.
Read more about this topic: Scavenger Receptor
Famous quotes containing the word function:
“It is not the function of our Government to keep the citizen from falling into error; it is the function of the citizen to keep the Government from falling into error.”
—Robert H. [Houghwout] Jackson (1892–1954)
“The mother’s and father’s attitudes toward the child correspond to the child’s own needs.... Mother has the function of making him secure in life, father has the function of teaching him, guiding him to cope with those problems with which the particular society the child has been born into confronts him.”
—Erich Fromm (1900–1980)
“My function in life is not to be a politician in Parliament: it is to get something done.”
—Bernadette Devlin (b. 1947)