Rift Valley Fever - Clinical Signs and Diagnosis

Clinical Signs and Diagnosis

In humans, the virus can cause several syndromes. Usually, sufferers have either no symptoms or only a mild illness with fever, headache, myalgia and liver abnormalities. In a small percentage of cases (< 2%), the illness can progress to hemorrhagic fever syndrome, meningoencephalitis (inflammation of the brain), or affecting the eye. Patients who become ill usually experience fever, generalized weakness, back pain, dizziness, and weight loss at the onset of the illness. Typically, patients recover within two to seven days after onset.

About 1% of human sufferers die of the disease. In livestock, the fatality level is significantly higher. Pregnant livestock infected with RVF abort virtually 100% of fetuses. An epizootic (animal disease epidemic) of RVF is usually first indicated by a wave of unexplained abortions.

Other signs in livestock include vomiting and diarrhoea, respiratory disease, fever, lethargy, anorexia and sudden death in young animals.

Diagnosis relies on viral isolation from tissues, or serological testing with an ELISA.

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