Queuine T RNA-ribosyltransferase

Queuine T RNA-ribosyltransferase

In enzymology, a queuine tRNA-ribosyltransferase (EC 2.4.2.29) is an enzyme that catalyzes the chemical reaction

-guanine + queuine -queuine + guanine

Thus, the two substrates of this enzyme are -guanine]] and queuine, whereas its two products are -queuine]] and guanine.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is -guanine:queuine tRNA-D-ribosyltransferase. Other names in common use include tRNA-guanine transglycosylase, guanine insertion enzyme, tRNA transglycosylase, Q-insertase, queuine transfer ribonucleate ribosyltransferase, transfer ribonucleate glycosyltransferase, tRNA guanine transglycosidase, guanine, queuine-tRNA transglycosylase, and tRNA-guanine:queuine tRNA-D-ribosyltransferase.

Read more about Queuine T RNA-ribosyltransferase:  Structural Studies