Co-protagonists
- Socorro Bonilla as Zulema Ruiz - Omar's wife, real mother of Lorena
- Alfonso Iturralde as Omar Armendáriz - Son of Hortensia
- Hector Ortega as Toribio Ugarte - Alonso's father
- Danna Paola as Bettina Aguilar Ugarte - Paula's daughter
- Mauricio Aspe as Arturo Sabogal Huerta
- Mike Biaggio as Chalo Carrasco - Sara's former lover and accomplice, villain (Killed by Sara)
- Marco Méndez as Bruno Palma (Killed by Sara)
- Luz Elena González as Diana Ruiz - Lorena's sister
- Bibelot Mansur as Rossy López Martínez - Julian's wife, daughter of Maruja
- Patricia Martínez as María Eugenia "Maruja" Martínez de Armendáriz - Jaime's former wife
- Sharis Cid as Paula Ugarte Solano - Alonso's sister, mother of Bettina
- Eduardo Rivera as Darío Aguilar
- Zully Keith as Catalina Huerta - Arturo's mother
- Dalilah Polanco as Greta
- Jose Carlos Femat as Julían Ruiz - Son of Zulema, Lorena's brother, Rossy's husband
- Alexandra Grana as Jacqueline Hernandez
- Adanely Nunez as Valeria - In love with Alonso
- Jose Manuel Lechuga as Vasco Armendáriz Amescua - Son of Jaime and Barbara
- María Alicia Delgado as Mother Trinidad
- Mercedes Vaughan as Mother Carmelita
- Nuria Bages as Mother Asunción
- Luis Xavier as Jaime Armendariz - Hortensia's son
- Mariana Ávila as Mónica Gaitán
- Elizabeth Aguilar as Maestra Rodríguez
- Abril Campillo as Dra. Noemí Serrano
- Dobrina Liubomirova as Silvia Mendiola Chávez
- Jorge Ortín as Raymundo Gaitán
- Polly as Fanny
- Jesús Zavala as Iván Liñán Mendiola
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