Quercetin 2,3-dioxygenase

In enzymology, a quercetin 2,3-dioxygenase (EC 1.13.11.24) is an enzyme that catalyzes the chemical reaction

quercetin + O₂ 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H+

Thus, the two substrates of this enzyme are quercetin and O₂, whereas its 3 products are 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate, CO, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O₂. The systematic name of this enzyme class is quercetin:oxygen 2,3-oxidoreductase (decyclizing). Other names in common use include quercetinase, and flavonol 2,4-oxygenase. It has 2 cofactors: iron, and Copper.