Quaternary Ammonium Cation - Health Effects

Health Effects

Quaternary ammonium compounds can display a range of health effects, amongst which are mild skin and respiratory irritation up to severe caustic burns on skin and gastro-intestinal lining (depending on concentration), gastro-intestinal symptoms (e.g., nausea and vomiting), coma, convulsions, hypotension and death.

They are thought to be the chemical group responsible for anaphylactic reactions that occur with use of neuromuscular blocking drugs during general anaesthesia in surgery. Quaternium-15 is the single most often found cause of allergic contact dermatitis of the hands (16.5% in 959 cases)

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