Quantitative Trait Locus - Interval Mapping

Interval Mapping

Lander and Botstein developed interval mapping, which overcomes the three disadvantages of analysis of variance at marker loci. Interval mapping is currently the most popular approach for QTL mapping in experimental crosses. The method makes use of a genetic map of the typed markers, and, like analysis of variance, assumes the presence of a single QTL. Each location in the genome is posited, one at a time, as the location of the putative QTL....

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Famous quotes containing the word interval:

    I was interested to see how a pioneer lived on this side of the country. His life is in some respects more adventurous than that of his brother in the West; for he contends with winter as well as the wilderness, and there is a greater interval of time at least between him and the army which is to follow. Here immigration is a tide which may ebb when it has swept away the pines; there it is not a tide, but an inundation, and roads and other improvements come steadily rushing after.
    Henry David Thoreau (1817–1862)