Pulmonary Toxicity Due To Medicinal Drugs
Within all classes of medicinal drugs that possibly can lead to pulmonary toxicity as a side effect, most pulmonary toxicity is due to chemotherapy for cancer.
Many medicinal drugs can lead to pulmonary toxicity. A few medicinal drugs can lead to pulmonary toxicity frequently (in medicine defined by international regulatory authorities such as the U.S. Food and Drug Administration and the EMEA as > 1% and < 10%) or very frequently (defined as > 10%). These medicinal drugs can include gold and nitrofurantoin, as well as the following drugs used in chemotherapy for cancer: Methotrexate, the taxanes (paclitaxel and docetaxel), gemcitabine, bleomycin, mitomycin C, busulfan, cyclophosphamide, chlorambucil, and nitrosourea (e.g., carmustine).
Also, some medicinal drugs used in cardiovascular medicine can lead to pulmonary toxicity frequently or very frequently. These include above all amiodarone, as well as beta blockers, ACE inhibitors (however, pulmonary toxicity of ACE inhibitors usually lasts only 3–4 months and then usually disappears by itself), procainamide, quinidine, tocainide, and minoxidil.
Both oncologists and cardiologists are well aware of possible pulmonary toxicity.
Read more about this topic: Pulmonary Toxicity
Famous quotes containing the words due, medicinal and/or drugs:
“It is the characteristic of great poems that they will yield of their sense in due proportion to the hasty and the deliberate reader. To the practical they will be common sense, and to the wise wisdom; as either the traveler may wet his lips, or an army may fill its water-casks at a full stream.”
—Henry David Thoreau (1817–1862)
“Our Indian said that he was a doctor, and could tell me some medicinal use for every plant I could show him ... proving himself as good as his word. According to his account, he had acquired such knowledge in his youth from a wise old Indian with whom he associated, and he lamented that the present generation of Indians “had lost a great deal.””
—Henry David Thoreau (1817–1862)
“Razors pain you;
Rivers are damp;
Acids stain you;
And drugs cause cramp.
Guns aren’t lawful;
Nooses give;
Gas smells awful;
You might as well live.”
—Dorothy Parker (1893–1967)