Weaknesses Addressed
- Ventilatory limitation
- Increased dead space ventilation
- Impaired gas exchange
- Increased ventilatory demands due to peripheral muscle dysfunction
- Gas exchange limitation
- Compromised functional inspiratory muscle strength
- Compromised inspiratory muscle endurance
- Cardiac dysfunction
- Increase in right ventricular afterload due to increased peripheral vascular resistance.
- Skeletal muscle dysfunction
- Average reduction in quadriceps strength decreased by 20-30% in moderate to severe COPD
- Reduction in the proportion of type I muscle fibres and an increase in the proportion of type II fibres compared to age matched normal subjects
- Reduction in capillary to fibre ratio and peak oxygen consumption
- Reduction in oxidative enzyme capacity and increased blood lactate levels at lower work rates compared to normal subjects
- Prolonged periods of under nutrition which results in a reduction in strength and endurance
- Respiratory muscle dysfunction
Read more about this topic: Pulmonary Rehabilitation
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