History
Understanding of the tertiary structure of proteins and their determinants, though important, represent a long standing issue in biochemistry. The first predicted structure of globular proteins was the cyclol model of Dorothy Wrinch, but this was quickly discounted as being inconsistent with experimental data. Modern methods are sometimes able to predict the tertiary structure de novo to within 5 Å for small proteins (<120 residues) and under favorable conditions, e.g., confident secondary structure predictions.
Read more about this topic: Protein Tertiary Structure
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“History has neither the venerableness of antiquity, nor the freshness of the modern. It does as if it would go to the beginning of things, which natural history might with reason assume to do; but consider the Universal History, and then tell us,—when did burdock and plantain sprout first?”
—Henry David Thoreau (1817–1862)
“It is my conviction that women are the natural orators of the race.”
—Eliza Archard Connor, U.S. suffragist. As quoted in History of Woman Suffrage, vol. 4, ch. 9, by Susan B. Anthony and Ida Husted Harper (1902)
“All history becomes subjective; in other words there is properly no history, only biography.”
—Ralph Waldo Emerson (1803–1882)