Pars Compacta - Function

Function

The function of the dopamine neurons in the substantia nigra pars compacta is complex. Contrary to what was thought initially it is not directly linked to movements. "Dopamine neurons are activated by novel, unexpected stimuli, by primary rewards in the absence of predictive stimuli and during learning". Dopamine neurons are thought to be involved in learning to predict which behaviours will lead to a reward (for example food or sex). In particular, it is suggested that dopamine neurons fire when a reward is greater than that previously expected; a key component of many reinforcement learning models. This signal can then be used to update the expected value of that action. Many drugs of abuse, such as cocaine, mimic this reward response—providing an explanation for their addictive nature.

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Famous quotes containing the word function:

    “... The state’s one function is to give.
    The bud must bloom till blowsy blown
    Its petals loosen and are strown;
    And that’s a fate it can’t evade
    Unless ‘twould rather wilt than fade.”
    Robert Frost (1874–1963)

    Every boy was supposed to come into the world equipped with a father whose prime function was to be our father and show us how to be men. He can escape us, but we can never escape him. Present or absent, dead or alive, real or imagined, our father is the main man in our masculinity.
    Frank Pittman (20th century)

    The intension of a proposition comprises whatever the proposition entails: and it includes nothing else.... The connotation or intension of a function comprises all that attribution of this predicate to anything entails as also predicable to that thing.
    Clarence Lewis (1883–1964)