Pancreatic cancer is a malignant neoplasm originating from transformed cells arising in tissues forming the pancreas. The most common type of pancreatic cancer, accounting for 95% of these tumors, is adenocarcinoma (tumors exhibiting glandular architecture on light microscopy) arising within the exocrine component of the pancreas. A minority arise from islet cells, and are classified as neuroendocrine tumors. The signs and symptoms that eventually lead to the diagnosis depend on the location, the size, and the tissue type of the tumor, and may include abdominal pain, lower back pain, and jaundice (if the tumor compresses the bile duct).
Pancreatic cancer is the fourth most common cause of cancer-related deaths in the United States and the eighth worldwide. Pancreatic cancer has a poor prognosis: for all stages combined, the 1- and 5-year relative survival rates are 25% and 6%, respectively; for local disease the 5-year survival is approximately 20% while the median survival for locally advanced and for metastatic disease, which collectively represent over 80% of individuals, is about 10 and 6 months respectively.
Read more about Pancreatic Cancer: Signs and Symptoms, Risk Factors, Diagnosis, Pathophysiology, Prevention, Prognosis
Famous quotes containing the word cancer:
“I’m beginning to believe that Killer Illiteracy ought to rank near heart disease and cancer as one of the leading causes of death among Americans. What you don’t know can indeed hurt you, and so those who can neither read nor write lead miserable lives, like Richard Wright’s character, Bigger Thomas, born dead with no past or future.”
—Ishmael Reed (b. 1938)