Oxidation of Primary Alcohols To Carboxylic Acids

The oxidation of primary alcohols to carboxylic acids is an important oxidation reaction in organic chemistry.

When a primary alcohol is converted to a carboxylic acid, the terminal carbon atom increases its oxidation state by four. Oxidants able to perform this operation in complex organic molecules, featuring other oxidation-sensitive functional groups, must possess substantial selectivity. The most common oxidants are potassium permanganate (KMnO4), Jones reagent, PDC in DMF, Heyns oxidation, ruthenium tetroxide (RuO4) and TEMPO.

Read more about Oxidation Of Primary Alcohols To Carboxylic Acids:  Potassium Permanganate, Jones Oxidation, PDC in DMF (Corey and Schmidt), Heyns Oxidation, Two-step Oxidation of Alcohols To Acids Via Isolated Aldehydes

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