Discovery of The Role of Pancreas in Diabetes
Minkowski worked with Josef von Mering on the study of diabetes at the University of Strasbourg. Their landmark study in 1889 in dogs induced diabetes by removing their pancreas. It was Minkowski who performed the operation and made the crucial link to recognize that the symptoms of the treated dogs were due to diabetes. Thus they were able to indicate that the pancreas contained regulators to control blood sugar; they also provided model for the study of diabetes. Their work led other doctors and scientists to pursue further research on the relation of the pancreas to diabetes, and ultimately resulted in the discovery of insulin as a treatment for the disease.
- Joseph von Mering, Oskar Minkowski: Diabetes mellitus nach Pankreasextirpation. Centralblatt für klinische Medicin, Leipzig, 1889, 10 (23): 393-394. Archiv für experimentelle Patholgie und Pharmakologie, Leipzig, 1890, 26: 37. It begins with, After removal of the pancreas dogs get diabetes. It starts sometime after the operation and will persist for weeks continuously until their death...
Read more about this topic: Oskar Minkowski
Famous quotes containing the words discovery of, discovery, role and/or pancreas:
“The discovery of Pennsylvania’s coal and iron was the deathblow to Allaire. The works were moved to Pennsylvania so hurriedly that for years pianos and the larger pieces of furniture stood in the deserted houses.”
—For the State of New Jersey, U.S. public relief program (1935-1943)
“The discovery of the North Pole is one of those realities which could not be avoided. It is the wages which human perseverance pays itself when it thinks that something is taking too long. The world needed a discoverer of the North Pole, and in all areas of social activity, merit was less important here than opportunity.”
—Karl Kraus (1874–1936)
“A few [women] warrant our attention not because they have the answer but because they have rejected the mentality that insists there must be one answer. What makes them role models is not how much or how little they work, how many or how few hats they wear, but rather how well they understand, and accept, that for all rewards there will be commensurate sacrifice; for all gains, some loss; for any pleasure, some pain.”
—Melinda M. Marshall (20th century)
“We don’t invent our natures. They’re issued to us along with our lungs, our pancreas and everything else.”
—Michael Mann, U.S. screenwriter. Hannibal Lechtor (Brian Cox)