Discovery of The Role of Pancreas in Diabetes
Minkowski worked with Josef von Mering on the study of diabetes at the University of Strasbourg. Their landmark study in 1889 in dogs induced diabetes by removing their pancreas. It was Minkowski who performed the operation and made the crucial link to recognize that the symptoms of the treated dogs were due to diabetes. Thus they were able to indicate that the pancreas contained regulators to control blood sugar; they also provided model for the study of diabetes. Their work led other doctors and scientists to pursue further research on the relation of the pancreas to diabetes, and ultimately resulted in the discovery of insulin as a treatment for the disease.
- Joseph von Mering, Oskar Minkowski: Diabetes mellitus nach Pankreasextirpation. Centralblatt für klinische Medicin, Leipzig, 1889, 10 (23): 393-394. Archiv für experimentelle Patholgie und Pharmakologie, Leipzig, 1890, 26: 37. It begins with, After removal of the pancreas dogs get diabetes. It starts sometime after the operation and will persist for weeks continuously until their death...
Read more about this topic: Oskar Minkowski
Famous quotes containing the words discovery of, discovery, role and/or pancreas:
“We are all humiliated by the sudden discovery of a fact which has existed very comfortably and perhaps been staring at us in private while we have been making up our world entirely without it.”
—George Eliot [Mary Ann (or Marian)
“One of the laudable by-products of the Freudian quackery is the discovery that lying, in most cases, is involuntary and inevitable—that the liar can no more avoid it than he can avoid blinking his eyes when a light flashes or jumping when a bomb goes off behind him.”
—H.L. (Henry Lewis)
“Whatever we’re doing, whoever we are, it isn’t enough. . . . Little wonder we have trouble finding role models to guide us through these shoals. No one less than God Herself could be all the things we’d like to be to all the people we’d like to feel approval from.”
—Melinda M. Marshall (20th century)
“We don’t invent our natures. They’re issued to us along with our lungs, our pancreas and everything else.”
—Michael Mann, U.S. screenwriter. Hannibal Lechtor (Brian Cox)