Discovery of The Role of Pancreas in Diabetes
Minkowski worked with Josef von Mering on the study of diabetes at the University of Strasbourg. Their landmark study in 1889 in dogs induced diabetes by removing their pancreas. It was Minkowski who performed the operation and made the crucial link to recognize that the symptoms of the treated dogs were due to diabetes. Thus they were able to indicate that the pancreas contained regulators to control blood sugar; they also provided model for the study of diabetes. Their work led other doctors and scientists to pursue further research on the relation of the pancreas to diabetes, and ultimately resulted in the discovery of insulin as a treatment for the disease.
- Joseph von Mering, Oskar Minkowski: Diabetes mellitus nach Pankreasextirpation. Centralblatt für klinische Medicin, Leipzig, 1889, 10 (23): 393-394. Archiv für experimentelle Patholgie und Pharmakologie, Leipzig, 1890, 26: 37. It begins with, After removal of the pancreas dogs get diabetes. It starts sometime after the operation and will persist for weeks continuously until their death...
Read more about this topic: Oskar Minkowski
Famous quotes containing the words discovery of, discovery, role and/or pancreas:
“The discovery of the North Pole is one of those realities which could not be avoided. It is the wages which human perseverance pays itself when it thinks that something is taking too long. The world needed a discoverer of the North Pole, and in all areas of social activity, merit was less important here than opportunity.”
—Karl Kraus (1874–1936)
“I have known no experience more distressing than the discovery that Negroes didn’t love me. Unutterable loneliness claimed me. I felt without roots, like a man without a country ...”
—Sarah Patton Boyle, U.S. civil rights activist and author. The Desegregated Heart, part 1, ch. 10 (1962)
“The role of the writer is not simply to arrange Being according to his own lights; he must also serve as a medium to Being and remain open to its often unfathomable dictates. This is the only way the work can transcend its creator and radiate its meaning further than the author himself can see or perceive.”
—Václav Havel (b. 1936)
“We don’t invent our natures. They’re issued to us along with our lungs, our pancreas and everything else.”
—Michael Mann, U.S. screenwriter. Hannibal Lechtor (Brian Cox)