Professional Boxing Record
| 39 Wins (30 knockouts, 9 decisions), 6 Losses (2 knockouts, 4 decisions), 0 Draws | |||||||
| Res. | Record | Opponnent | Type | Round | Date | Location | Notes |
| Loss | 39-6 | Manny Pacquiao | TKO | 8 (12), 3:00 | 2008-12-06 | MGM Grand Garden Arena, Las Vegas, Nevada | A non-title welterweight bout. |
| Win | 39-5 | Steve Forbes | UD | 12 | 2008-05-03 | The Home Depot Center, Carson, California | A non-title light middleweight bout. Fight at 150-pound catch weight. |
| Loss | 38-5 | Floyd Mayweather, Jr. | SD | 12 | 2007-05-05 | MGM Grand Garden Arena, Las Vegas, Nevada | Lost WBC Light Middleweight title. |
| Win | 38-4 | Ricardo Mayorga | TKO | 6 (12), 1:25 | 2006-05-06 | MGM Grand Garden Arena, Las Vegas, Nevada | Won WBC Light Middleweight title. |
| Loss | 37-4 | Bernard Hopkins | KO | 9 (12), 1:38 | 2004-09-18 | MGM Grand Garden Arena, Las Vegas, Nevada | Lost WBO Middleweight title. For WBC, WBA (Super), IBF & The Ring Middleweight titles. |
| Win | 37-3 | Felix Sturm | UD | 12 | 2004-06-05 | MGM Grand Garden Arena, Las Vegas, Nevada | Won WBO Middleweight title. |
| Loss | 36-3 | Shane Mosley | UD | 12 | 2003-09-13 | MGM Grand Garden Arena, Las Vegas, Nevada | Lost WBC, WBA (Super), IBA & The Ring Light Middleweight titles. |
| Win | 36-2 | Luis Ramon Campas | TKO | 7 (12), 2:54 | 2003-05-03 | Mandalay Bay Events Center, Las Vegas, Nevada | Retained WBC, WBA (Super) & The Ring Light Middleweight titles. |
| Win | 35-2 | Fernando Vargas | TKO | 11 (12), 1:48 | 2002-09-14 | Mandalay Bay Events Center, Las Vegas, Nevada | Retained WBC and won WBA (Super), IBA & vacant The Ring Light Middleweight titles. |
| Win | 34-2 | Javier Castillejo | UD | 12 | 2001-06-23 | MGM Grand Garden Arena, Las Vegas, Nevada | Won WBC Light Middleweight title. |
| Win | 33-2 | Arturo Gatti | TKO | 5 (10), 1:16 | 2001-03-24 | MGM Grand Garden Arena, Las Vegas, Nevada | A non-title welterweight bout. |
| Loss | 32-2 | Shane Mosley | SD | 12 | 2000-06-17 | Staples Center, Los Angeles, California | Lost WBC & IBA Welterweight titles. |
| Win | 32-1 | Derrell Coley | KO | 7 (12), 3:00 | 2000-02-26 | Madison Square Garden, New York, New York | Won vacant IBA Welterweight title. |
| Loss | 31-1 | Félix Trinidad | MD | 12 | 1999-09-18 | Mandalay Bay Events Center, Las Vegas, Nevada | Lost WBC & Lineal Welterweight titles. For IBF Welterweight title. |
| Win | 31-0 | Oba Carr | TKO | 11 (12), 0:55 | 1999-05-22 | Mandalay Bay Events Center, Las Vegas, Nevada | Retained WBC & Lineal Welterweight titles. |
| Win | 30-0 | Ike Quartey | SD | 12 | 1999-02-13 | Thomas & Mack Center, Las Vegas, Nevada | Retained WBC & Lineal Welterweight titles. |
| Win | 29-0 | Julio César Chávez | RTD | 8 (12), 3:00 | 1998-09-18 | Thomas & Mack Center, Las Vegas, Nevada | Retained WBC & Lineal Welterweight titles. |
| Win | 28-0 | Patrick Charpentier | TKO | 3 (12), 1:56 | 1998-06-13 | Sun Bowl, El Paso, Texas | Retained WBC & Lineal Welterweight titles. |
| Win | 27-0 | Wilfredo Rivera | TKO | 8 (12), 2:48 | 1997-12-06 | Caesars Atlantic City, Atlantic City, New Jersey | Retained WBC & Lineal Welterweight titles. |
| Win | 26-0 | Héctor Camacho | UD | 12 | 1997-09-13 | Thomas & Mack Center, Las Vegas, Nevada | Retained WBC & Lineal Welterweight titles. |
| Win | 25-0 | David Kamau | KO | 2 (12), 2:54 | 1997-06-14 | Alamodome, San Antonio, Texas | Retained WBC & Lineal Welterweight titles. |
| Win | 24-0 | Pernell Whitaker | UD | 12 | 1997-04-12 | Thomas & Mack Center, Las Vegas, Nevada | Won WBC & Lineal Welterweight titles. |
| Win | 23-0 | Miguel Ángel González | UD | 12 | 1997-01-18 | Thomas & Mack Center, Las Vegas, Nevada | Retained WBC & Lineal Light Welterweight titles. |
| Win | 22–0 | Julio César Chávez | TKO | 4 (12), 2:37 | 1996-06-07 | Caesars Palace, Las Vegas, Nevada | Won WBC & Lineal Light Welterweight titles. |
| Win | 21-0 | Darryl Tyson | KO | 2 (10), 2:38 | 1996-02-09 | Caesars Palace, Las Vegas, Nevada | A non-title lightweight bout. |
| Win | 20-0 | Jesse James Leija | TKO | 2 (12), 3:00 | 1995-12-15 | Madison Square Garden, New York, New York | Retained WBO Lightweight title. |
| Win | 19-0 | Genaro Hernandez | RTD | 6 (12), 3:00 | 1995-09-09 | Caesars Palace, Las Vegas, Nevada | Retained WBO Lightweight title. |
| Win | 18-0 | Rafael Ruelas | TKO | 2 (12), 1:43 | 1995-05-06 | Caesars Palace, Las Vegas, Nevada | Retained WBO & won IBF Lightweight titles. |
| Win | 17-0 | John John Molina | UD | 12 | 1995-02-18 | MGM Grand Garden Arena, Las Vegas, Nevada | Retained WBO Lightweight title. |
| Win | 16-0 | John Avila | TKO | 9 (12), 1:07 | 1994-12-10 | Grand Olympic Auditorium, Los Angeles, California | Retained WBO Lightweight title. |
| Win | 15-0 | Carl Griffith | TKO | 3 (12), 1:02 | 1994-11-18 | MGM Grand Garden Arena, Las Vegas, Nevada | Retained WBO Lightweight title. |
| Win | 14-0 | Jorge Páez | KO | 2 (12), 0:39 | 1994-07-29 | MGM Grand Garden Arena, Las Vegas, Nevada | Won vacant WBO Lightweight title. |
| Win | 13-0 | Giorgio Campanella | TKO | 3 (12), 2:22 | 1994-05-27 | MGM Grand Garden Arena, Las Vegas, Nevada | Retained WBO Super Featherweight title. |
| Win | 12-0 | Jimmy Bredahl | RTD | 10 (12), 3:00 | 1994-03-05 | Grand Olympic Auditorium, Los Angeles, California | Won WBO Super Featherweight title. |
| Win | 11-0 | Narciso Valenzuela | KO | 1 (10), 2:25 | 1993-10-30 | America West Arena, Phoenix, Arizona | |
| Win | 10-0 | Angelo Nunez | RTD | 4 (10), 3:00 | 1993-08-27 | Beverly Wilshire Hotel, Beverly Hills, California | |
| Win | 9-0 | Renaldo Carter | TKO | 6 (10), 2:10 | 1993-08-14 | Hollywood Casino Bay St. Louis, Hancock, Mississippi | |
| Win | 8-0 | Troy Dorsey | RTD | 1 (10), 3:00 | 1993-06-07 | Thomas & Mack Center, Las Vegas, Nevada | |
| Win | 7-0 | Frank Avelar | TKO | 4 (10), 2:00 | 1993-05-08 | Caesars Tahoe, Stateline, Nevada | |
| Win | 6-0 | Mike Grable | UD | 8 | 1993-04-06 | Blue Cross Arena, Rochester, New York | |
| Win | 5-0 | Jeff Mayweather | TKO | 4 (8), 1:35 | 1993-03-13 | Hilton Hotel, Las Vegas, Nevada | |
| Win | 4-0 | Curtis Strong | TKO | 4 (6), 1:40 | 1993-02-06 | San Diego Sports Arena, San Diego, California | |
| Win | 3-0 | Paris Alexander | TKO | 2 (6), 1:52 | 1993-01-03 | Hollywood Palladium, Los Angeles, California | |
| Win | 2-0 | Clifford Hicks | KO | 1 (6), 1:15 | 1992-12-12 | America West Arena, Phoenix, Arizona | |
| Win | 1-0 | Lamar Williams | KO | 1 (6), 1:42 | 1992-11-23 | Great Western Forum, Inglewood, California | Professional debut. |
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