Orgel's First Rule
"Whenever a spontaneous process is too slow or too inefficient a protein will evolve to speed it up or make it more efficient."
This "rule" comments on the fact that there is a great number of proteins in all organisms which fulfil a number of different functions through modifying chemical or physical processes. An example would be an enzyme that catalyses a chemical reaction that would take place too slow to benefit an organism without being sped up by this enzyme.
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“To rule is not so much a question of the heavy hand as the firm seat.”
—José Ortega Y Gasset (1883–1955)