Major Intersections
- Note: OR 99 uses many different highways (see Oregon highways and routes); the milepoint column shows mileage along these highways, not adjusted for equations, with the highway number in front. Not all interchanges on I-5 are shown. For a complete list of interchanges, see the Interstate 5 exit list.
| County | Location | Milepoint | Destinations | Notes |
|---|---|---|---|---|
| Jackson | 63 24.11 | I-5 south | ||
| Ashland | 63 20.5 | OR 66 to I-5 – Lakeview, Klamath Falls | ||
| Medford | 63 5.56 | OR 62 east / OR 238 west to I-5 / OR 140 – Rogue Valley Mall, Crater Lake, Jacksonville | ||
| 63 0.26 | Blackwell Road | Former US 99 north | ||
| 63 0.00 1 35.80 |
I-5 south – Medford | South end of I-5 overlap | ||
| 1 40.82 271Y 3.02 |
I-5 north – Grants Pass | North end of I-5 overlap | ||
| 271Y 2.76 | Blackwell Road | Former US 99 south | ||
| Gold Hill | 271 2.36 | OR 234 east – Crater Lake | South end of OR 234 overlap | |
| 271 -0.30 60 14.50 |
To I-5 (via OR 234 west) | North end of OR 234 overlap | ||
| 60 12.63 | I-5 – Medford, Grants Pass | Interchange | ||
| Josephine | Grants Pass | 60 0.18 | To I-5 (via Redwood Spur) | |
| 60 0.00 25 -0.07 |
US 199 south – Crescent City | South end of US 199 overlap | ||
| 25 -0.94 | To I-5 / F Street | Former Redwood Spur | ||
| 25 -1.00 | E Street | Former Rogue River Loop Highway | ||
| 25 -2.63 | Scoville Road | Northbound exit and southbound entrance | ||
| 25 -2.85 1 58.25 |
I-5 south – Medford | South end of I-5 overlap | ||
| Douglas | Canyonville | 1 98.31 | I-5 north – Roseburg | North end of I-5 overlap |
| 3rd Street – Days Creek, Crater Lake | Former OR 227 south | |||
| Yokum Road – Riddle | ||||
| 1 101.15 | I-5 south – Canyonville | South end of I-5 overlap | ||
| 1 103.98 | I-5 north – Myrtle Creek, Roseburg | North end of I-5 overlap | ||
| Pruner Road – Riddle | ||||
| 1 108.27 | I-5 south – Grants Pass | South end of I-5 overlap | ||
| 1 112.28 | I-5 north – Roseburg | North end of I-5 overlap | ||
| Winston | 35 73.37 | OR 42 west, Coquille, Coos Bay | South end of OR 42 overlap | |
| 35 76.22 | OR 42 east to I-5 – Roseburg, Grants Pass | North end of OR 42 overlap | ||
| I-5 south – Grants Pass | Interchange | |||
| Roseburg | 138 -0.31 | OR 138 west to I-5 – West Roseburg | South end of OR 138 overlap | |
| 138 0.00 | OR 138 east (North Umpqua Highway) – Diamond Lake, Crater Lake | North end of OR 138 overlap | ||
| Sutherlin | To OR 138 / I-5 – Elkton | |||
| 1 140.05 | I-5 south – Roseburg | South end of I-5 overlap; southbound exit and northbound entrance | ||
| 1 150.51 | I-5 north – Eugene | North end of I-5 overlap | ||
| Drain | 45 50.25 | OR 38 west – Ocean Beaches, Reedsport, Coos Bay | South end of OR 38 overlap | |
| 45 56.37 | Curtin Road – Anlauf, Lorane | Former Territorial Highway | ||
| Anlauf | 45 57.33 1 162.39 |
I-5 south – Roseburg | North end of OR 38 overlap; south end of I-5 overlap | |
| Lane | 1 168.37 226 20.05 |
I-5 north – Portland | North end of I-5 overlap; northbound exit and southbound entrance | |
| Creswell | 226 5.78 | Oregon Avenue – Lorane | ||
| 226 5.74 | To I-5 (via OR 222) – Eugene, Roseburg | |||
| 226 0.23 | Franklin Boulevard | Former US 99 north | ||
| 226 0.00 18 0.07 |
OR 58 east (Willamette Highway) – Oakridge, Klamath Falls | |||
| 18 0.31 1 188.57 |
I-5 south – Roseburg | South end of I-5 overlap | ||
| 1 189.87 | 30th Avenue – South Eugene (OR 225) | Former US 99 north | ||
| Eugene | 1 192.27 1W 126.38 |
I-5 north – Portland | North end of I-5 overlap; northbound exit and southbound entrance | |
| 1W 126.02 | Riverview Street | Interchange; no southbound entrance | ||
| 1W 125.93 | OR 126 Bus. east – Springfield |
Interchange; south end of OR 126 Bus. overlap; southbound exit and northbound entrance; former US 99 south | ||
| 1W 124.02 | To I-105 / I-5 / Coburg Road – Springfield | Interchange | ||
| 1W 123.29 | I-105 / OR 126 east to I-5 – Springfield | Interchange; north end of OR 126 Bus. overlap; south end of OR 126 overlap | ||
| 1W 122.97 | Blair Boulevard | Former Junction City-Eugene Highway | ||
| 1W 122.19 | OR 126 west – Veneta, Elmira, Florence | North end of OR 126 overlap | ||
| 1W 118.42 | To OR 126 / I-5 / Beltline Highway (OR 569) – Florence, Springfield | Interchange | ||
| 1W 111.28 | OR 36 – Cheshire, Florence | |||
| Junction City | 1W 109.76 | 1st Avenue to High Pass Road – Santa Clara | Former Junction City-Eugene Highway | |
| 1W 108.76 | OR 99E north / OR 99W north – Albany, Portland, Corvallis, McMinnville |
- This list is incomplete; you can help by expanding it.
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