History
The olfactory tubercle was first described by Albert von Kölliker in 1896 who studied them in rats. Since then, there have been several histological and histochemical studies (Koob 1978; Millhouse 1984) done in this area to identify it in other rodents, cats, humans, non-human primates, and other species. Similar studies were done by several authors to find the cell composition and innervations to and from other regions in the OT. Over the years several other methods have been eemployed to find the possible functions and role of the OT in the brain. These began with lesion studies (Gervais 1979; Oades 1981; Asher & Aghajanian 1974; Koob 1978) because the olfactory tuber is too small of an area to record from. Recent developments in technology have made it possible to now place electrodes in this area of the brain so recordings can be done in animals in an awake and vigilant state while they participate in several behavioral studies (Wesson & Wilson 2010; Ikemoto 2002; Ikemoto 2003; Doty 1991)
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