Families
A nomenclature system has been devised for the olfactory receptor family and is the basis for the official Human Genome Project (HUGO) symbols for the genes that encode these receptors. The names of individual olfactory receptor family members are in the format "ORnXm" where:
- OR is the root name (Olfactory Receptor superfamily)
- n = an integer representing a family (e.g., 1-56) whose members have greater than 40% sequence identity,
- X = a single letter (A, B, C, ...) denoting a subfamily (>60% sequence identity), and
- m = an integer representing an individual family member (isoform).
For example OR1A1 is the first isoform of subfamily A of olfactory receptor family 1.
Members belonging to the same subfamily of olfactory receptors (>60% sequence identity) are likely to recognize structurally similar odorant molecules.
Two major classes of olfactory receptors have been identified in humans:
- class I (fish-like receptors) OR families 51-56
- class II (tetrapod specific receptors) OR families 1-13
Read more about this topic: Olfactory Receptor
Famous quotes containing the word families:
“Children from humble families must be taught how to command just as other children must be taught how to obey.”
—Friedrich Nietzsche (1844–1900)
“The man who promised to reinforce American families is now eager to pull the plug on Big Bird and Barney.”
—Leslie Harris, U.S. political activist. As quoted in Newsweek magazine, p. 23 (December 19, 1994)
“Nostalgia is one of the great enemies of clear thinking about the family. The disruption of families in the nineteenth century through death, separation, and other convulsions of an industrializing economy was much more catastrophic than we imagine.”
—Joseph Featherstone (20th century)