Discovery
In 2004 Linda B. Buck and Richard Axel won the Nobel Prize in Physiology or Medicine for their work on olfactory receptors. In 2006 it was shown that another class of odorant receptors exist for volatile amines. This class of receptors consists of the trace amine-associated receptors (TAAR) with the exception of TAAR1 which is a receptor for thyronamines.
Unfortunately, as with many other GPCRs, there is still a lack of experimental structures at atomic level for olfactory receptors and structural information is based on homology modeling methods.
Read more about this topic: Olfactory Receptor
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—George Berkeley (1685–1753)
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