Major Intersections
| County | Location | Mile | Destinations | Notes | |
|---|---|---|---|---|---|
| South Carolina state line | 0.0 | SC 49 south (Charlotte Highway) – York | Southern terminus | ||
| Mecklenburg | Charlotte | 3.5 | NC 160 (Steele Creek Road) | ||
| 7.7 | I-485 (Seddon Rusty Goode Jr. Freeway) to I-85 / I-77 – Greensboro, Columbia, SC | Diamond interchange; I-485 exit 1 | |||
| 11.6 | Route 4 (Billy Graham Parkway) to I-77 south / US 21 south – Columbia, SC | Access to Charlotte/Douglas International Airport; Access to I-77/US 21 south | |||
| 11.8 | I-77 north / US 21 north – Statesville | I-77 exit 6; Partial cloverleaf interchange; northbound exit only | |||
| 14.4 | NC 160 south (West Boulevard) | Northern terminus of NC 160 | |||
| 15.2 | NC 27 east (Morehead Street) – Albemarle | South end of concurrency with NC 27 | |||
| 15.3 | I-277 / US 74 east – Monroe | Eastbound access only | |||
| 15.4 | US 29 south / NC 27 west (Morehead Street) – Gastonia, Lincolnton | South end of concurrency with US 29; North end of concurrency with NC 27 | |||
| 16.8 | I-277 / NC 16 north (Brookshire Freeway) to I-77 / I-85 – Columbia, Gastonia, Greensboro, Lowesville | I-277 outer loop and NC 16 northbound exit only via W. 12th Street | |||
| 19.9 | Route 4 (Sugar Creek Road) to I-85 – Gastonia, Salisbury | I-85 exit 41 | |||
| 23.4 | US 29 north (Tryon Street) – Concord | North end of concurrency with US 29 | |||
| 24.1 | NC 24 (W.T. Harris Boulevard) – Albemarle | Partial cloverleaf interchange | |||
| 26.4 | I-485 to I-85 / I-77 – Greensboro, Statesville | I-485 exit 33; Partial cloverleaf interchange | |||
| Cabarrus | Concord | 37.0 | US 601 – Monroe, Salisbury | Partial cloverleaf interchange | |
| Mt. Pleasant | 42.9 | NC 73 – Concord, Albemarle | Full interchange | ||
| Stanly | Richfield | 54.7 | US 52 (Church Street) – Albemarle, Lexington | ||
| 58.6 | NC 8 south – New London | South end of concurrency with NC 8 | |||
| Davidson | Newsom | 62.4 | NC 8 north – Lexington | North end of concurrency with NC 8 | |
| Handy | 66.5 | NC 109 – Troy, Denton | Diamond interchange | ||
| Randolph | 71.0 | NC 47 west – Denton, Lexington | Eastern terminus of NC 47 | ||
| Asheboro | 84.2 | US 64 west (Dixie Drive) – Lexington | South end of concurrency with US 64 | ||
| 84.4 | Future I-73 / Future I-74 / US 220 – Rockingham, Greensboro | Cloverleaf interchange | |||
| 85.3 | US 220 Bus. (Fayetteville Street) |
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| 85.7 | NC 159 south (Zoo Parkway) – Seagrove | Access to North Carolina Zoo | |||
| 87.1 | NC 42 – Coleridge | ||||
| Ramseur | 95.0 | NC 22 north – Climax | South end of wrong-way concurrency with NC 22 | ||
| 95.3 | NC 22 south (Colridge Road) – Carthage | North end of wrong-way concurrency with NC 22 | |||
| 95.9 | US 64 east (Jordan Road) – Siler City, Pittsboro | North end of concurrency with US 64 | |||
| Liberty | 103.1 | US 421 – Greensboro, Sanford | Diamond interchange | ||
| Alamance | Burlington | 123.1 | I-85 / I-40 – Charlotte, Winston-Salem, Durham, Raleigh | I-85 exit 145; Diamond interchange | |
| 123.5 | NC 54 west (Chapel Hill Road) / NC 100 west (Maple Avenue) – Whitsett | South end of concurrency with NC 54; Eastern terminus of NC 100 | |||
| Graham | 124.5 | NC 87 north (Elm Street) – Reidsville | South end of wrong-way concurrency with NC 87 | ||
| 125.1 | NC 87 south (Main Street) – Fayetteville | North end of wrong-way concurrency with NC 87 | |||
| 125.4 | NC 54 east (Harden Street) – Raleigh | North end of concurrency with NC 54 | |||
| Haw River | 127.2 | US 70 west (Main Street) – Greensboro | South end of concurrency with US 70 | ||
| 128.2 | US 70 east (Main Street) – Durham | North end of concurrency with US 70 | |||
| Pleasant Grove | 135.2 | NC 62 – Archdale, Yanceyville | |||
| 137.8 | NC 119 – Swepsonville, Hightowers | ||||
| Orange | 144.3 | NC 86 south – Chapel Hill | South end of concurrency with NC 86 | ||
| Caswell | Prospect Hill | 144.7 | NC 86 north – Hillsborough | North end of concurrency with NC 86 | |
| Person | Roxboro | 159.8 | US 158 west (Leasburg Road) – Yanceyville | South end of concurrency with US 158 | |
| 160.3 | NC 57 (Concord Road) – Milton | South end of wrong-way concurrency with NC 57 | |||
| 160.6 | US 158 east / US 501 south / NC 57 south (S. Madison Boulevard) – Oxford, Durham, Hillsborough | North end of concurrency with US 158; South end of concurrency with US 501; North End of wrong-way concurrency with NC 57 | |||
| 162.2 | US 501 north (Main Street) – South Boston | North end of concurrency with US 501 | |||
| Granville | 177.6 | NC 96 south (Little Batterwhite Road) – Oxford | South end of concurrency with NC 96 | ||
| Virginia state line | 177.8 | SR 49 / SR 96 (Florence Avenue) – Virgilina, Clarksville | Northern terminus | ||
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Read more about this topic: North Carolina Highway 49
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