Non-competitive Inhibition - Terminology

Terminology

It is important to note that, while all non-competitive inhibitors bind at allosteric sites-- i.e. any site on the enzyme other than its active site-- not all inhibitors that bind at allosteric sites are non-competitive inhibitors. In fact, allosteric inhibitors may act as competitive, non-competitive, or uncompetitive inhibitors.

Many sources continue to conflate these two terms, or state the definition of allosteric inhibition as the definition for non-competitive inhibition.

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