Nitrogen Mustard - Examples

Examples

The original nitrogen mustard drug, mustine (HN2), is no longer commonly in use. Other nitrogen mustards developed as treatments include cyclophosphamide, chlorambucil, uramustine, ifosfamide, melphalan, and bendamustine. Bendamustine has recently reemerged as a viable chemotheraputic treatment.

Nitrogen mustards that can be used for chemical warfare purposes are tightly regulated. Their weapon designations are:

  • HN1: Bis(2-chloroethyl)ethylamine
  • HN2: Bis(2-chloroethyl)methylamine
  • HN3: Tris(2-chloroethyl)amine

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