Nicotinic Versus Muscarinic Activity
| Comparison of cholinergic agonists | ||||
|---|---|---|---|---|
| Substance | Receptor specificity | Hydrolysis by acetylcholinesterase |
Comments | |
| Muscarinic | Nicotinic | |||
| Choline | +++ | +++ | ++ | Essential nutrient |
| Acetylcholine | +++ | +++ | +++ | Endogenous ligand |
| Carbachol | ++ | +++ | - | Used in the treatment of glaucoma |
| Methacholine | +++ | + | ++ | |
| Bethanechol | +++ | - | - | Used in bladder and gastrointestinal hypotonia. |
| Muscarine | +++ | - | - | Natural alkaloid found in certain mushrooms. Cause of mushroom poisoning |
| Nicotine | - | +++ | - | Natural alkaloid found in the tobacco plant. |
| Pilocarpine | ++ | - | - | Used in glaucoma |
| Oxotremorine | ++ | - | - | |
Read more about this topic: Nicotinic Agonist
Famous quotes containing the word activity:
“The superstition respecting power and office is going to the ground. The stream of human affairs flows its own way, and is very little affected by the activity of legislators. What great masses of men wish done, will be done; and they do not wish it for a freak, but because it is their state and natural end.”
—Ralph Waldo Emerson (1803–1882)