A nicotine patch is a transdermal patch that releases nicotine into the body through the skin. It is used as an aid in nicotine replacement therapy (NRT), a process for smoking cessation. The first published study of the pharmacokinetics of a transdermal nicotine patch in humans was authored by Jed E. Rose, Ph.D., Murray E. Jarvik, M.D., Ph.D. and K. Daniel Rose, M.D., in the journal Drug and Alcohol Dependence (vol. 13, pp.209-213, 1984). This was followed by publication of results of a study of smokers showing that a transdermal nicotine patch reduced craving for cigarettes (Rose JE, Herskovic JE, Trilling Y and Jarvik ME, Clinical Pharmacology and Therapeutics, vol. 38, pp. 450-456, 1985). Dr. Frank T. Etscorn III, filed a patent on January the 23rd 1985 and was issued the patent on July 1, 1986 (U.S. Patent #4,597,961). The University of California filed a competing patent application nearly 3 years after Dr. Etscorn's filing on February the 19th, 1988, which was granted on May 1st 1990 (U.S. Patent #4,920,989).
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Famous quotes containing the words nicotine and/or patch:
“Pull out a Monte Cristo at a dinner party and the political liberal turns into the nicotine fascist.”
—Martyn Harris (b. 1952)
“I sing a hero’s head, large eye
And bearded bronze, but not a man,
Although I patch him as I can
And reach through him almost to man.”
—Wallace Stevens (1879–1955)