Diseases
Any disorder that compromises the synaptic transmission between a motor neuron and a muscle cell is categorized under the umbrella term neuromuscular diseases. These disorders can be inherited or acquired. These disorders vary in their severity and their mortality. In general, most tend to be caused by mutations or autoimmune disorders. Autoimmune disorders, in the case of neuromuscular diseases, tend to be humoral mediated, B cell mediated, and result in an antibody against a motor neuron or muscle fiber protein that interferes with synaptic transmission or signaling.
Read more about this topic: Neuromuscular Junction
Famous quotes containing the word diseases:
“Even diseases have lost their prestige, there aren’t so many of them left.... Think it over ... no more syphilis, no more clap, no more typhoid ... antibiotics have taken half the tragedy out of medicine.”
—Louis-Ferdinand Céline (1894–1961)
“The fantasies inspired by TB in the last century, by cancer now, are responses to a disease thought to be intractable and capricious—that is, a disease not understood—in an era in which medicine’s central premise is that all diseases can be cured.”
—Susan Sontag (b. 1933)
“Arrogance, pedantry, and dogmatism ... the occupational diseases of those who spend their lives directing the intellects of the young.”
—Henry S. Canby (1878–1961)