Neural Development - Synapse Elimination

Synapse Elimination

Several motorneurones compete for each neuromuscular junction, but only one survives until adulthood. Competition in vitro has been shown to involve a limited neurotrophic substance that is released, or that neural activity infers advantage to strong post-synaptic connections by giving resistance to a toxin also released upon nerve stimulation. In vivo it is suggested that muscle fibres select the strongest neuron through a retrograde signal.

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Famous quotes containing the word elimination:

    The kind of Unitarian
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    Robert Frost (1874–1963)