Achievements
NIAID has established a reputation for being on the cutting edge of scientific progress both through its intramural labs and through the research it funds at academic institutions. For example, NIAID collaborations with various partners led to the development of FDA-approved vaccines for influenza (FluMist), hepatitis A (Havrix), and rotavirus (RotaShield). NIAID also was instrumental in the development and licensure of acellular pertussis vaccines, conjugate vaccines for Streptococcus pneumoniae and Haemophilus influenzae type b or Hib, and a preventive therapy for respiratory syncytial virus or RSV (Synagis). Additionally, NIAID partnerships with industry and academia have led to the advancement of diagnostic tests for several important infectious diseases, including malaria (ParaSight F), tuberculosis (GeneXpert MTB/RIF), and norovirus (Ridascreen Norovirus 3rd Generation EIA).
NIAID is a recognized pioneer in the study of HIV/AIDS and has helped improve standards of care of HIV-infected people in the United States and abroad. For example, its research on mother-to-child transmission (MTCT) of HIV has paved the way for new health interventions that have saved many lives. In 1994, a landmark study co-sponsored by NIAID demonstrated that the drug AZT, given to HIV-infected women who had little or no prior antiretroviral therapy (ART), reduced the risk of MTCT by two-thirds. This and other findings since then have helped reduce perinatal HIV infections in the United States by more than 90 percent, according to the Centers for Disease Control and Prevention.
In 1999, an NIAID-funded study in Uganda found that two oral doses of the inexpensive drug nevirapine—one given to HIV-infected mothers at the onset of labor and another to their infants soon after birth—reduced MTCT by half when compared with a similar course of AZT. Subsequent clinical trials, including some funded by NIAID, showed that AIDS drugs also can reduce the risk of MTCT through breast milk. These and other studies have led to World Health Organization recommendations that can help prevent MTCT while allowing women in resource-limited settings to breastfeed their infants safely.
More recently, NIAID-funded scientists found that testing at-risk infants for HIV and then giving ART immediately to those who test positive dramatically reduces rates of illness and death. HIV-infected infants were four times less likely to die if given ART immediately after they were diagnosed with HIV, when compared with the standard of care (beginning ART in infants when they showed signs of HIV illness or a weakened immune system).
This finding helped influence the World Health Organization (WHO) to change its guidelines for treating HIV-infected infants. The guidelines now strongly recommend starting ART in all children under age 2 immediately after they have been diagnosed with HIV, regardless of their health status.
Read more about this topic: National Institute Of Allergy And Infectious Diseases
Famous quotes containing the word achievements:
“Our achievements speak for themselves. What we have to keep track of are our failures, discouragements, and doubts. We tend to forget the past difficulties, the many false starts, and the painful groping. We see our past achievements as the end result of a clean forward thrust, and our present difficulties as signs of decline and decay.”
—Eric Hoffer (1902–1983)
“Fathers are still considered the most important “doers” in our culture, and in most families they are that. Girls see them as the family authorities on careers, and so fathers’ encouragement and counsel is important to them. When fathers don’t take their daughters’ achievements and plans seriously, girls sometimes have trouble taking themselves seriously.”
—Stella Chess (20th century)
“Freedom of enterprise was from the beginning not altogether a blessing. As the liberty to work or to starve, it spelled toil, insecurity, and fear for the vast majority of the population. If the individual were no longer compelled to prove himself on the market, as a free economic subject, the disappearance of this freedom would be one of the greatest achievements of civilization.”
—Herbert Marcuse (1898–1979)