Mycoplasma Genitalium - Treatment

Treatment

The CDC recommends using one of these treatments, in this order of prevalence (the first is known to be the most effective, the others are alternative treatments)

  • Azithromycin 1 g orally in a single dose
  • Doxycycline 100 mg orally twice a day for 7 days
  • Erythromycin base 500 mg orally four times a day for 7 days
  • Erythromycin ethylsuccinate 800 mg orally four times a day for 7 days
  • Ofloxacin 300 mg orally twice a day for 7 days
  • Levofloxacin 500 mg orally once daily for 7 days

However, this study Azithromycin Failure in Mycoplasma genitalium Urethritis says that "...doxycycline and levofloxacin have substantial failure rates..." and "...Recurrent urethral symptoms following azithromycin therapy only occurred in persons with persistent M. genitalium infection and resolved with moxifloxacin."

So moxifloxacin appears to be an alternative treatment after one of the other treatments have already failed (Azithromycin 1g is the preferred first-line treatment).

Read more about this topic:  Mycoplasma Genitalium

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