Multiple Birth - Higher Order Multiples

Higher Order Multiples

High orders of multiple births (three or more offspring in one birth) may result in a combination of fraternal (genetically different) and identical (genetically identical) siblings. The latter are also called super twins. For example, a set of quadruplets may consist of two sets of identical twins; in such a case each child has one identical and two fraternal siblings. This happens when multiple eggs are fertilized and one or more these subsequently divides into two fetuses. By analogy with monozygotic and dizygotic twins, such a combination is called dizygotic triplets. The Kübler triplets (see Elisabeth Kübler-Ross) were of this type.

Identical triplets or quadruplets are very rare and result when the original fertilized egg splits and then one of the resultant cells splits again (for triplets) or, even more rarely, a further split occurs (for quadruplets). Alternatively the original fertilized egg can split twice (to produce four embryos) and all four may survive, to produce identical quadruplets, or one of the embryos may not survive and result in triplets.

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