Prevalence
There are only about 14 reported cases of Morvan’s Syndrome in the English Literature. With only a limited number of reported cases, the complete spectrum of the Central Nervous System (CNS) symptomatology has not been well established. The natural history of Morvan’s is highly variable. Two cases have been reported to remit spontaneously. Others have required a combination of plasmapheresis and long term immunosuppression, although in one of these cases the patient died shortly after receiving Plasma Exchange (PE). Other fatalities without remission have been described by, amongst others, Morvan himself.
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