In developmental biology, a morphogenetic field is a group of cells able to respond to discrete, localized biochemical signals leading to the development of specific morphological structures or organs. The spatial and temporal extent of the embryonic fields are dynamic, and within the field is a collection of interacting cells out of which a particular organ is formed. As a group, the cells within a given morphogenetic field are constrained — i.e. cells in a limb field will become a limb tissue, those in a cardiac field will become heart tissue. Importantly, however, the specific cellular programming of individual cells in a field is flexible: an individual cell in a cardiac field can be redirected via cell-to-cell signaling to replace specific damaged or missing cells. Imaginal discs in insect larvae are examples of morphogenetic fields.
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Famous quotes containing the word field:
“You cannot go into any field or wood, but it will seem as if every stone had been turned, and the bark on every tree ripped up. But, after all, it is much easier to discover than to see when the cover is off. It has been well said that “the attitude of inspection is prone.” Wisdom does not inspect, but behold.”
—Henry David Thoreau (1817–1862)