Molecular Biology - Techniques of Molecular Biology - Macromolecule Blotting and Probing

Macromolecule Blotting and Probing

The terms northern, western and eastern blotting are derived from what initially was a molecular biology joke that played on the term Southern blotting, after the technique described by Edwin Southern for the hybridisation of blotted DNA. Patricia Thomas, developer of the RNA blot which then became known as the northern blot actually didn't use the term. Further combinations of these techniques produced such terms as southwesterns (protein-DNA hybridizations), northwesterns (to detect protein-RNA interactions) and farwesterns (protein-protein interactions), all of which are presently found in the literature.

Read more about this topic:  Molecular Biology, Techniques of Molecular Biology

Famous quotes containing the words blotting and/or probing:

    I’m a good scholar when it comes to reading but a blotting kind of writer when you give me a pen.
    —J.M. (John Millington)

    Industrial societies turn their citizens into image-junkies; it is the most irresistible form of mental pollution. Poignant longings for beauty, for an end to probing below the surface, for a redemption and celebration of the body of the world. Ultimately, having an experience becomes identical with taking a photograph of it.
    Susan Sontag (b. 1933)