Meconium Aspiration Syndrome - Treatment

Treatment

Amnioinfusion, a method of thinning thick meconium that has passed into the amniotic fluid through pumping of sterile fluid into the amniotic fluid, has not shown a benefit in treating MAS . Until recently it had been recommended that the throat and nose of the baby be suctioned by the delivery attendant as soon as the head is delivered. However, new studies have shown that this is not useful and the revised Neonatal Resuscitation Guidelines published by the American Academy of Pediatrics no longer recommend it. When meconium staining of the amniotic fluid is present and the baby is born depressed, it is recommended by the guidelines that an individual trained in neonatal intubation use a laryngoscope and endotracheal tube to suction meconium from below the vocal cords.

If the condition worsens to a point where treatments are not affecting the newborn as they should, extracorporeal membrane oxygenation (ECMO) can be necessary to keep the infant alive.

Lucinactant (Surfaxin) is used as a treatment of MAS. Albumin-lavage has not demonstrated to benefit outcomes of MAS. Steroid use has not demonstrated to benefit the outcomes of MAS.

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