Prognosis
Prognosis is generally poor (average case-fatality rate of all MVD outbreaks to date = 82%). If a patient survives, recovery may be prompt and complete, or protracted with sequelae, such as orchitis, hepatitis, uveitis, parotitis, desquamation or alopecia. Importantly, MARV is known to be able to persist in some survivors and to either reactivate and cause a secondary bout of MVD or to be transmitted via sperm, causing secondary cases of infection and disease.
Of the 252 people who contracted Marburg during the 2004–2005 outbreak in Angola, 227 died, for a case fatality rate of 90%.
Although all age groups are susceptible to infection, children are more rarely infected. In the 1998–2000 Congo epidemic, only 8% of the cases were children less than 5 years old.
Read more about this topic: Marburg Virus Disease