Other
- Lost Souls (Doves album), the 2000 debut album by British band Doves, and the title track
- Lost Souls (The Raindogs album), the 1990 debut album by American roots rock band The Raindogs
- Lost Souls (online game), a MUD, or text-based online role-playing game
- Earth 2150: Lost Souls, an expansion to the computer game, Earth 2150
- Dark Fall: Lost Souls, the third installment in the Dark Fall adventure game series
- Lost Soul, a monster from the Doom series of video games
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