Lmna

LMNA

Identifiers Symbols LMNA; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; PRO1 External IDs OMIM: 150330 MGI: 96794 HomoloGene: 41321 ChEMBL: 1293235 GeneCards: LMNA Gene

Gene Ontology
Molecular function	• structural molecule activity • protein binding
Cellular component	• nucleus • nuclear envelope • lamin filament • nuclear lamina • nucleoplasm • cytoplasm • intermediate filament • nuclear matrix • perinuclear region of cytoplasm
Biological process	• apoptotic process • cellular component disassembly involved in execution phase of apoptosis • activation of signaling protein activity involved in unfolded protein response • nuclear envelope organization • spermatogenesis • muscle organ development • regulation of cell migration • establishment or maintenance of microtubule cytoskeleton polarity • endoplasmic reticulum unfolded protein response • protein localization to nucleus • sterol regulatory element binding protein import into nucleus • regulation of apoptotic process • ventricular cardiac muscle cell development • cellular response to hypoxia • positive regulation of cell aging
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 4000 16905 Ensembl ENSG00000160789 ENSMUSG00000028063 UniProt P02545 P48678 RefSeq (mRNA) NM_001257374.1 NM_001002011.2 RefSeq (protein) NP_001244303.1 NP_001002011.2 Location (UCSC) Chr 1:
156.05 – 156.11 Mb Chr 3:
88.48 – 88.51 Mb PubMed search

Lamin A/C also known as LMNA is a protein that in humans is encoded by the LMNA gene. Lamin A/C belongs to the lamin family of proteins.