2003
- Anima: Age of the Robots by Johnny Tay 2003-2006, revamped in 2011
- A Modest Destiny by Sean Howard January 1, 2003 – August 2, 2005
- Suburban Tribe by John Lee January 2003 – ..
- Dinosaur Comics by Ryan North February 1, 2003 – ..
- A Softer World by Joey Comeau and Emily Horne February 7, 2003 – ..
- Least I Could Do by Ryan Sohmer and Lar DeSouza (previously with Chad WM. Porterand Trevor Adams) February 10, 2003 – ..
- Idiot Box by Matt Bors February 2003 – ..
- Girly by Josh Lesnick April 6, 2003 – September 16, 2010
- No Rest for the Wicked by Andrea L. Peterson April 20, 2003 – ..
- Wondermark by David Malki May 2003 – ..
- Antihero for Hire by Mark Shallow June 1, 2003 – ..
- Count Your Sheep by Adrian 'Adis' Ramos June 11, 2003 – ..
- Badmash by Sandeep Sood, Nimesh Patel and Sanjay Shah June 30, 2003 – ..
- Zap! by Chris Layfield and Pascalle July 13, 2003 – ..
- Questionable Content by Jeph Jacques August 2, 2003 – ..
- Loxie & Zoot by Stephen Crowley August 4, 2003 – ..
- Haiku Circus by Ken Samamoto September 9, 2003 – ..
- The Order of the Stick by Rich Burlew September 30, 2003 – ..
- Smithson by Shaenon K. Garrity et al. September 2003 – ..
- Twisted Kaiju Theater by Shin Goji October 22, 2003 – ..
- The Adventures of Dr. McNinja by Chris Hastings 2003 – ..
- Alpha Shade by Joseph and Chris Brudlos 2003 – ..
- Applegeeks by Mohammad "Hawk" Haque and Ananth Panagariya 2003 – ..
- Hetalia: Axis Powers by Hidekaz Himaruya 2003 –
- Inverloch by Sarah Ellerton 2003 – September 24, 2007
- L'il Mell and Sergio by Shaenon K. Garrity et al. 2003 – ..
- Star Cross'd Destiny by Juno 2003 – October 18, 2005
- Unspeakable Vault (Of Doom) by Goomi 2003 – ..
- Is This Tomorrow? by Kelly Shane and Woody Compton 2003 – ..
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