EastEnders
- Donna Andrews
- played by Alison Senior (2001); Paula Jennings (2002)
- Lucy Beale
- played by Eva Brittin-Snell (1993–1996); Casey Anne Rothery (1996–2004); Melissa Suffield (2004–2010); Hetti Bywater (2012—)
- Peter Beale
- played by Francis Brittin-Snell (1993–1996); Alex Stevens (1997–1998); Joseph Shade (1998–2004); James Martin (2004–2006); Thomas Law (2006–2010)
- Steven Beale
- played by Edward Farrell (1989–1990); Stuart Stevens (1992–1996); Edward Savage (1997–2002); Aaron Sidwell (2007–2008)
- Derek Branning
- played by Terence Beesley (1996); Jamie Foreman (2011—12)
- Lauren Branning
- played by Madeline Duggan (2006–2010); Jacqueline Jossa (2010—)
- Rachel Branning
- played by Sukie Smith (2006); Pooky Quesnel (2007–2010)
- Suzy Branning
- played by Julie Christian-Young (1996); Maggie O'Neill (2008)
- Clare Butcher
- played by Caroline O'Neill (1989); Lucy Foxall (2002)
- Janine Butcher
- played by Rebecca Michael (1989–1993); Alexia Demetriou (1993–1996); Charlie Brooks (1999—)
- Liam Butcher
- played by Sonny Bottomley (1998–1999); Jack and Tom Godolphin (1999–2000); Gavin and Mitchell Vaughan (2002); Nathaniel Gleed (2002–2004); James Forde (2008—)
- Ashley Cotton
- played by Rossi Higgins (1993); Frankie Fitzgerald (2000–2001)
- Zoe Cotton
- played by Elizabeth Chadwick (1993); Tara Ellis (2000–2001)
- Edwina Dunn
- played by Patricia Maynard (2001); Gay Hamilton (2005)
- Mark Fowler
- played by David Scarboro (1985–1987); Todd Carty (1990–2003)
- Martin Fowler
- played by Jon Peyton Price (1985–1996); James Alexandrou (1996–2007)
- Vicki Fowler
- played by Emma Henry (1986–1988); Samantha Leigh Martin (1988–1995); Scarlett Alice Johnson (2003–2004)
- Billie Jackson
- played by Devon Anderson (1993–1997, 2010); Bluey Robinson (2004)
- Ashraf Karim
- played by Tony Wredden (1987); Aftab Sachak (1988–1990)
- Ben Mitchell
- played by Matthew Silver (1996–1998); Morgan Whittle (1999–2000); Charlie Jones (2006–2010); Joshua Pascoe (2010–2012)
- Courtney Mitchell
- played by Charlotte Michael (1997–1998), Carissa and Josephine O'Meara (1998–1999); Megan Jossa (2006)
- Louise Mitchell
- played by Rachel Cox (2001–2003); Danni Bennatar (2008); Brittany Papple (2010)
- Peggy Mitchell
- played by Jo Warne (1991); Barbara Windsor (1994–2010)
- Sam Mitchell
- played by Danniella Westbrook (1990–2000, 2009–2010); Kim Medcalf (2002–2005)
- Lydia Simmonds
- played by Margaret Tyzack (2011), Heather Chasen (2011)
- Annie Smith
- played by Zara Posener (1985–1986); Samantha Crown (1986–1988)
- Summer Swann
- played by Daisy Fitter (2007); Abbie Hackworth (2007); Harry Swash (2007); Isabella and Rebecca Hegarty (2007–2009)
- Cindy Williams
- played by Ella Wortley (1998); Cydney Parker (1998); Eva Sayer (2007)
Read more about this topic: List Of Soap Opera Recasts