- M
- M2001
- M4
- Machine code
- MAD (Michigan Algorithm Decoder)
- MAD/I
- Magik
- Magma
- make
- Maple
- MAPPER (Unisys/Sperry) now part of BIS
- MARK-IV (Sterling/Informatics) now VISION:BUILDER of CA
- Mary
- MASM Microsoft Assembly x86
- Mathematica
- MATLAB
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- Maxima (see also Macsyma)
- Max (Max Msp - Graphical Programming Environment)
- MaxScript internal language 3D Studio Max
- Maya (MEL)
- MDL
- Mercury
- Mesa
- Metacard
- Metafont
- MetaL
- Microcode
- MicroScript
- MIIS
- MillScript
- MIMIC
- Mirah
- Miranda
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- MIVA Script
- ML
- Moby
- Model 204
- Modelica
- Modula
- Modula-2
- Modula-3
- Mohol
- MOO
- Mortran
- Mouse
- MPD
- MSIL - deprecated name for CIL
- MSL
- MUMPS
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