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- Patti LaBelle
- Ladysmith Black Mambazo
- Emeril Lagasse
- Lamb Chop sings alphabet song
- Burt Lancaster
- Sean Landeta, one special: Landeta, a New York Giants player, appears during the celebrity performance of "Put Down the Duckie" in Put Down the Duckie: The Sesame Street Special.
- Michael Landon
- Nathan Lane
- Queen Latifah
- Matt Lauer, explaining what he can do with a newspaper, also interviewing Cookie Monster about his decision to eat fruit
- Laurien
- Jude Law, demonstrating the word "cling"
- Spike Lee
- John Legend
- John Leguizamo
- Jay Leno
- Shari Lewis
- Ed Lipton
- Listen My Brother
- Little Richard
- LL Cool J
- Rebecca Lobo
- Los Lobos
- Eva Longoria, demonstrating the word "exquisite"
- Julia Louis-Dreyfus
- MC Lyte
Read more about this topic: List Of Guest Stars On Sesame Street