Pharmacology and Medical Uses of Free Lipoic Acid
Today, R/S-LA and RLA are widely available as over-the-counter nutritional supplements in the United States in the form of capsules, tablets and aqueous liquids, and have been branded as antioxidants. This label has recently been challenged. In Japan, LA is marketed primarily as a "weight loss" and "energy" supplement. The relationships between supplemental doses and therapeutic doses have not been clearly defined. Because lipoic acid is not an essential nutrient, no Recommended Daily Allowance (RDA) has been established.
For use in dietary supplement materials and compounding pharmacies, the USP has established an official monograph for racemic R/S-LA.
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