- Ambiorix (1st century B.C.) - Leader of the Gaulish Eburones against Julius Caesar.
- Frieda Brepoels, (1955) - Politician
- Robert Cailliau, (1947) - Co-inventor of the World Wide Web, together with Tim Berners-Lee.
- Willy Claes, (1938) - Politician; former Secretary General of NATO.
- Ingrid Daubechies, - (1954) Physicist and mathematician.
- Neel Doff, (1858–1942) - Writer.
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- Jan van Eyck, (ca.1390-1441) - Flemish painter.
- Adrien de Gerlache, (1866–1934) - Former Antarctica explorer.
- St Lambert, - Early Christian saint.
- St Servatius, - Early Christian saint.
- Barthélémy de Theux de Meylandt, (1794–1874) - Politician; former Prime Minister.
- Hendrik van Veldeke, - First writer from the Low Countries known by name (c. 1140-c. 1190).
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